Aloe vera is one of the oldest known herbal medicine that can be traced back in ancient Egypt. Aloe vera plant was depicted on stone carvings and in Eber's papyrus in 16th Century BCE, found in burial grounds of deceased pharoahs..
Aloe vera was historically used to heal wounds and treat various skin conditions, Aloe was also taken orally as a laxative. Nowadays, aloe extract is still popularly used as a home remedy for skin problems such as psoriasis, burns, sunburns, insect bites and others. Aloe vera can be found in many skin products such as lotions, gels and sunblocks. Other folkloric uses include treatment of arthritis, asthma, diabetes, epilepsy and osteoarthritis.
Aloe Vera is a herb that grows in warm climates and is widely distributed in Philippines, India, and Africa. Aloe Vera is widely used as traditional herbal medicine in China, Japan, Russia, South Africa, the United States, Jamaica, Latin America and India. Aloe Vera is frequently cited as being used in herbal medicine for its anti-inflammatory, regenerative, anti-bacterial and anti-fungal and healing properties.
Aloe Vera is a herb that grows up to 35 cm in height with green leaves. Aloe Vera leaves are about 6 cm wide that grows up tapering with spiny margins. Aloe Vera flower grows erect from the herb to as much as twice the height of the plant. Aloe Vera flowers are yellow to red yellow in color that grows to about 2cm.
Aloe Vera is traditionally used to treat the following skin conditions
Aloe Vera juice or the fleshy leaf is applied directly to the affected skin, providing relief and believed to improve healing.
Fresh Aloe Vera juice or sap are massaged to the affected scalp and let it stay for a few minutes before washing.
Aloe vera has several active constituents and most of them have therapeutic implications for disease prevention and treatment through the modulation of various biological and genetic activities. The possible mechanisms of actions of Aloe vera are described as follows:
A study that isolated di(2)-ethylhexyl)phthalate (DEHP) from Aloe vera found that Aloe Vera exhibited growth inhibition against three leukemic cell lines and reduced AF-2-induced mutagenicity. DEHP was considered the active principle responsible for the anti-leukemic and anti-mutagenic effects in vitro.
Extracts of Aloe vera Linne have been found to exhibit cytotoxicity against human tumour cell lines.
Study isolated a major carbohydrate fraction from the gell of Aloe vera leaf. It has been claimed to accelerate wound healing, immune stimulation and have anti-cancer and anti-viral effects. Study showed acemannan an extract found from Aloe vera stimulate cytokine production, nitric oxide release. The production of cytokines IL-6 and TNF-alpha were acemannan dose-dependent. The results suggest acemannan may function, in part, through macrophage activation.
Studies suggest that acemannan, a polysaccharide extracted from Aloe vera gel, could affect bone formation. Acemannan could function as a bioactive molecule inducing bone formation by stimulating BMSCs proliferation, differentiation into osteoblasts, and extracellular matrix synthesis. Acemannan extracted from Aloe vera could be a candidate for natural biomaterial for bone regeneration.
Study showed percentage of both objective tumor regressions and disease control was significantly higher in patients concomitantly treated with Aloe than with chemotherapy alone. Study suggest Aloe may be beneficial to use with chemotherapy to increase efficacy in terms of both tumore regression and survival time.
Study showed antigenotoxic potentials of aloe and suggests a potential use in prevention of DNA damage caused by chemical agents.
Study characterized a new immunostimulatory polysaccharide, Aloeride, from commercial aloe vera juice
Aloe vera are widely cultivated and generally grown in pots. It can be bought it from your local horticulturist and at time at home depot shops as ornamental plant. Aloe vera is also widely used as ingredient in cosmetic and herbal preparations.
Aloe vera leaves contain a clear gel that is often used as a topical ointment. The green part of the Aloe leaf that surrounds the gel can be used to produce a juice or a dried substance (called latex) that is taken by mouth.
NCCAM Clearinghouse. The NCCAM Clearinghouse provides information on CAM and NCCAM, including publications and searches of Federal databases of scientific and medical literature. The Clearinghouse does not provide medical advice, treatment recommendations, or referrals to practitioners.
Toll-free in the U.S.: 1-888-644-6226 TTY (for deaf and hard-of-hearing callers): 1-866-464-3615 Web site: nccam.nih.gov E-mail: email@example.com
A service of the National Library of Medicine (NLM), PubMed® contains publication information and (in most cases) brief summaries of articles from scientific and medical journals. CAM on PubMed®, developed jointly by NCCAM and NLM, is a subset of the PubMed® system and focuses on the topic of CAM.
Web site: www.ncbi.nlm.nih.gov/sites/entrez
CAM on PubMed® : nccam.nih.gov/research/camonpubmed/