Health Benefits of Evening Primrose for Atopic Dermatitis (Eczema)
A study published in the British Journal of Dermatology, 1987 entitled “Evening primrose oil in the treatment of atopic eczema: effect on clinical status, plasma phospholipid fatty acids and circulating blood prostaglandins” has reported that in a double-blind trial patients with atopic eczema received either oral evening primrose oil or placebo for 12 weeks. Those who were given evening primrose oil showed statistically significant improvement in the overall severity and grade of inflammation and in the percentage of the body surface involved by eczema as well as in dryness and itch.
http://www.ncbi.nlm.nih.gov/pubmed/3307886
Health Benefits of Evening Primrose for Premenstrual syndrome (PMS)
In a report published in Medical Journal of Australia, 1990 entitled “Evening primrose oil and treatment of premenstrual syndrome”; the therapeutic effectiveness of evening primrose oil in the relief of 10 symptoms associated with premenstrual syndrome (PMS) as well as menstrual symptoms was studied in 38 women. The findings indicate that the improvement experienced by the women with moderate PMS was solely a placebo effect.
http://www.ncbi.nlm.nih.gov/pubmed/2201888
Evening Primrose Health Benefits for Rheumatoid arthritis (RA)
In a report from Annals of the Rheumatic Diseases, 1989 entitled “Evening primrose oil in rheumatoid arthritis: changes in serum lipids and fatty acids” showed that there was a decrease in serum eicosapentaenoic acid and a corresponding increase in arachidonic acid concentrations in patients with rheumatoid arthritis when administered with evening primrose oil. This result suggests that evening primrose oil has favorable effects in patients with rheumatoid arthritis.
http://www.ncbi.nlm.nih.gov/pubmed/3307886
Health Benefits of Evening Primrose for Reynaud’s Phenomenon
In the Journal of Thrombosis and Haemostasis, 1985, a report entitled “Evening primrose oil (Efamol) in the treatment of Raynaud's phenomenon: a double blind study” have shown that patients who were given evening primrose oil showed symptomatically improvement if compared to a control group taking placebo. This was not matched however by any change in objective assessment of blood flow, although changes in platelet behavior and blood prostanoids were observed.
http://www.ncbi.nlm.nih.gov/pubmed/4082084
Evening Primrose may have Anti Cancer Health Benefits
In a study published in the Journal of Agricultural and Food Chemistry, 2011 entitled “Polyphenols from evening primrose (Oenothera paradoxa) defatted seeds induce apoptosis in human colon cancer Caco-2 cells” have shown that the polyphenols extracted from evening primrose may be an apoptosis inducer in human colorectal adenocarcinoma Caco-2 and HT-29 cell lines and in rat normal intestinal IEC-6 cells..
http://www.ncbi.nlm.nih.gov/pubmed/21627076
Health Benefits of Evening Primrose to Diabetic Patients
In a study entitled “Evening primrose oil and fish oil in non-insulin-dependent-diabetes” the effects of two anti-thrombotic and anti-lipidemic oils, evening primrose oil and fish oil, on glucose and lipid metabolism, prostaglandin (PG) levels and body composition were studied in patients with non-insulin-dependent diabetes. The results suggest that these oil treatments are useful in improving abnormal lipid and thromboxane (TX)A2 metabolism in diabetic patients.
http://www.ncbi.nlm.nih.gov/pubmed/8415806
Evening primrose as Breast pain Treatment
In a study published in Alternative Medicine Review, 2011, entitled “Vitamin E and evening primrose oil for management of cyclical mastalgia: a randomized pilot study” have shown that the daily doses of 1,200 IU vitamin E and 3,000 mg evening primrose when taken for six months have improved the pain control in women with cyclical mastalgia, likewise decreasing the severity of its symptoms.
http://www.ncbi.nlm.nih.gov/pubmed/20359269
Evening primrose may Offer Protective Health Benefits against Heart Diseases
In a study published in the Journal of Cardiovascular Pharmacology, 2011 “Effect of evening primrose oil and omega-3 polyunsaturated Fatty acids on the cardiovascular risk of celecoxib in rats” have shown that the extract of evening primrose can significantly decreased platelet aggregation and collagen-induced thrombocytopenia in rats administered with Celecoxib that known to elevate BP and increased the risk of thrombogenesis. The study suggests that a combination of celecoxib and the selected natural supplements is suggested as a novel approach to minimize cardiovascular risk caused by celecoxib.
http://www.ncbi.nlm.nih.gov/pubmed/21499116
Evening primrose May Have Antioxidative Health Benefit for the Liver.
In a study published in Food and Chemical Toxicology, 2011, entitled “The effects of evening primrose oil on lipid peroxidation induced by sub acute aflatoxin exposure in mice” have shown that evening primrose oil have antioxidative effect against lipid peroxidation in cases of subacute aflatoxin (AF) intoxication induced in mice
http://www.ncbi.nlm.nih.gov/pubmed/21600263
Potential Health Benefits of Evening Primrose for Multiple Sclerosis Patients
In a study published in the Medical Hypotheses, 1979 entitled “Multiple sclerosis: the rational basis for treatment with colchicine and evening primrose oil” suggests that based on preliminary results the combined therapy of evening primrose oil and colchicine may be of considerable value in Multiple sclerosis (MS) treatment. http://www.ncbi.nlm.nih.gov/pubmed/313499