Anti-leukemic / Anti-Mutagenic : Study isolated di(2-ethylhexyl)phthalate (DEHP) from Aloe vera. It exhibited growth inhibition against three leukemic cell lines and reduced AF-2-induced mutagenicity. DEHP was considered the active principle responsible for the anti-leukemic and anti-mutagenic effects in vitro.
Acemannan / Macrophage Activation : Study isolated a major carbohydrate fraction from the gell of Aloe vera leaf. It has been claimed to accelerate wound healing, immune stimulation and have anti-cancer and anti-viral effects. Study showed acemannan stimulate cytokine production, nitric oxide release. The production of cytokines IL-6 and TNF-alpha were acemannan dose-dependent. The results suggest acemannan may function, in part, through macrophage activation.
Biochemotherapy: Study showed percentage of both objective tumor regressions and disease control was significantly higher in patients concomitantly treated with Aloe than with chemotherapy alone. Study suggest Aloe may be beneficial to use with chemotherapy to increase efficacy in terms of both tumore regression and survival time.
Antigenotoxic : Study showed antigenotoxic potentials of aloe and suggests a potential use in prevention of DNA damage caused by chemical agents.
Aloe-emodin / Anticancer / Antiproliferative : Study sh owed aloe-emodin inhibited cell proliferation and induced apoptosis in two human liver cancer cell lines, but with different antiproliferative mechanisms. Results suggest aloe-emodin may be useful in liver cancer prevention.
Aloeride / Immunostimulatory Activity : Study characterized a new immunostimulatory polysaccharide, Aloeride, from commercial aloe vera juice